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Acylcarnitine also functions as a regulator of numerous key enzymes and ion channels, influencing ion handling mechanisms, including the flux of Na + , Ca 2+ , and K + [120]
doi: 10.1016/j.jpeds.2016.10.019 23
doi: 10.1038/s41588-021-00852-9
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5a,b), corresponding to the inability of KG, l-carnitine or acetylcarnitine to rescue histone acetylation following treatment with the HAT inhibitor (Extended Data Fig
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