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degree research who would like to acknowledge Abdul Wali Khan University Mardan (AWKUM), Pakistan for the financial support via studentship

3.5.2 Inadequate precision in metabolic regulation Emerging evidence highlights the multi-organ (hepaticrenalintestinal) coordination of urate metabolism, yet existing pharmacotherapies predominantly target single nodes (e.g., XO or URAT1)

While HDL cholesterol levels were maintained, participants who consumed almonds experienced clinically meaningful reductions in systolic blood pressure and Framingham cardiovascular risk scores, suggesting that almonds may play an important role in supporting heart health

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Nutrients known to support gut heath, mucus production, support tight junctions and secretory immunoglobulin type A (SIgA) levels include: L-glutamine fuels gut cells and boosts immunity Coconut oil/MCTs antibacterial/antifungal Bone broth / gelatine / collagen Vitamins D3 and A increase SigA Aloe vera/liquorice/quercetin Digestive enzymes Apple cider vinegar / betaine HCl supplements/high dose ascorbic acid increase natural stomach acid N-acetyl glucosamine anti-inflammatory, helps protect the lining of the stomach and intestines FMS may present with protein malabsorption issues FMS patients appear to have low BCAA (leucine, isoleucine, and valine) Diet and lifestyle The diet recommended to those with fibromyalgia should consist of simple, healthy and unadulterated foods, with junk foods and foods that are processed and highly refined being completely eliminated, as they are commonly linked to the triggering of symptoms