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Simultaneously, carotenoids accumulate in the stratum corneum, producing a gradual yellow-orange hue that becomes visible over time, particularly in low-melanin and sun protected areas such as the palms or inner arms (Figure 5)

Int J Tissue React 1999;21(1):1-6 [abstract] Virmani MA, Biselli R, Spadoni A, Rossi S, Corsico N, Calvani M, Fattorossi A, De Simone C, Arrigoni-Martelli E

The mitochondrion probably started off as a free-living cell which was engulfed by a larger cell and began a symbiotic existence, remaining rather independent from its host cell: mitochondria still carry their own DNA and divide independently of the cell

The concentrations of RNAs were determined with an Agilent 2,100 Bioanalyzer (Agilent Technologies Co., Ltd., Beijing, China)

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