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Administering drugs in a non- phosphorylated form, may improve cell entrance of a drug, since the cell membrane is poorly permeable to phosphorylated drugs

[DOI] [PubMed] [Google Scholar] 136.Matias MI, et al

319 , 126544 (2020) de Almeida Ferraz, N

Study of 32 cases with in situ hybridization

The kidney toxicity mechanism, specifically the breakdown of D-amino acids by renal enzymes, would likely make extended continuous use problematic

While a bone marrow biopsy was not conducted in this instance, it is generally not required for diagnosing vitamin B12 deficiency unless there is a concern for hematologic malignancies