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Description
SHED-exos inhibit the expression of markers associated with damage to the glands, such as autophagy, pyroptosis, NETosis, ferroptosis, necroptosis, and oxidative apoptosis

The upstream regulatory factors FDX1 and LIAS are critical in this process

2020 Aug;287(15):3150-3160

Its established mechanism of action continues to support mechanistic investigations into nicotinamide methylation pathways and the broader role of NNMT within cellular regulatory networks.

Furthermore, a key feature of the disease is the disrupted crosstalk between mitochondria and peroxisomes

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