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Later, as a young doctor, Sikiric worked in rural areas of the country, where he sometimes had to ration medical equipment and personnel

On the other hand, hypoxia can promote HIF1-mediated transcription of lactate dehydrogenase (LDH) and SLC7A11, activate intracellular lactate accumulation and cystine uptake, and promote tumor resistance to ferroptosis through the lactate/GPX4 pathway [193]

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Lancet Oncol (2021) 22(11):1597608
