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Discard vial 28 days after first use

Its side effect profile is generally mild, with most users reporting only injection site irritation or fatigue

the product information notes that refrigeration can cause a color change (darker yellow) which does not affect safety or effectiveness

Tell your prescribing doctor if you have any of these conditions, which can increase B12 shot side effects: An allergy to cobalt Kidney disease Severe megaloblastic anemia Side Effects from B12 Shots The most common B12 shot side effect is swelling at the injection site

Deficiency can cause numbness, tingling, and cognitive fog

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