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24 Compared with solvent treatment, populations of control (EV) RNAi animals treated with metabolite have significantly greater fragmentation characterized by circularly shaped mitochondria, which is potentially indicative of increased mitophagic activity due to decreased mitochondrial fission and more rapid turnover of mitochondria (Figures 5a and b)

uncertain randomization assignment [86], variability among vitamin D doses, types of administration and dosing schedules [82, 83, 85, 86] or the absence of measured serum 25(OH)D concentrations at baseline [83, 85]

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