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2017 meta-analysis: A systematic review and meta-analysis of nine randomized controlled trials showed that ALCAR supplementation significantly decreased depressive symptoms compared to placebo (standardized mean difference 1.10, 95% CI 1.65 to 0.56), with effects comparable to established antidepressants like fluoxetine, particularly in older adults or those with treatment-resistant depression [5][30]

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However, its use in gestational diabetes a condition that affects 4.6%-9.2% of all pregnancies in the US (141) has not been well studied

Marchesini G, Bianchi G, Merli M, et al

2015;63(2 Suppl 1):1-12