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71 OhJ.YounC

Dransk, Martin

doi: 10.1530/EC-19-0557 17 National Institute on Drug Abuse

1 In preclinical studies, treatment of mouse adipocytes with 5-Amino-1MQ resulted in a concentration-dependent increase in NAD+ levels (approximately 1.2 to 1.6-fold higher than controls), which is significant for metabolic homeostasis and cellular health

[ 423 ] BACH1 transcriptionally enhances FOSL2, thereby inducing the M2 macrophage phenotype through activating the TGF/SMAD signaling to facilitate the transformation of lung fibroblasts into myofibroblasts, and BACH1 deficiency alleviates BLMmediated pulmonary fibrosis