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Importantly, the secretory component of secretory IgA impairs its ability to bind to FcRI and stimulate NETosis, and therefore minimizes the risk of antibody-mediated immunopathology, making it a favourable target for induction by mucosal SARS-CoV-2 vaccines designed to elicit IgA responses at the site of infection 76

doi: 10.1016/j.addr.2014.04.005

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Animals and Surgery Twelve adult C57BL/6J mice ( n = 12, 6 females, 6 males
