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Metabolism : Carbamazepine: Extensive hepatic metabolism, mostly by CYP3A4 to an active metabolite, carbamazepine-10,11-epoxide

Considering the multifactorial nature of TMAO generation, many strategies can be pursued to reduce the level of TMA/TMAO in patients with CVDs, such as lifestyle changes, use of antibiotics and functional foods, development of related inhibitors, and improvement of gut microbiota ( Supplementary Table 4 )

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Mammalian and human studies showed that dyslipidaemia is accompanied frequently by inflammation 34

To view a copy of this license, visit About this article Cite this article Melone, M., Valentino, A., Margarucci, S