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Also, the insulin/insulin growth factor-1 signaling pathway is involved in the anti- Plasmodium response of mosquitoes (Pakpour et al., 2014), and RNA interference pathways (RNAi), which are discussed in greater detail in section 5.5, are essential components of the antiviral response

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The highest consumption of EDs and the highest sales values of this type of products are observed in the US, Vietnam, Cuba, the UK, Thailand, Mexico, Australia, Germany, Poland, and Saudi Arabia [13]

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