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Additionally, ROS-induced cysteine glutathionylation and its modulation have been shown to be the key regulators of IL-1beta bioactivity by preventing the irreversible ROS-elicited deactivation [111]

Umaa, P., Jean-Mairet, J., Moudry, R., Amstutz, H

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Additionally, treatment with -tocopherol appeared safe at the indicated doses, suggesting that AHA is not a common feature of antioxidants