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Neuroprotective effect of caffeine in Alzheimers disease

2004b;26:99106

Hass and Barnstable found that knocking out Mitochondrial Uncoupling Protein 2 (UCP2) in astrocytes, a glial cell that interacts with RGCs, restored respiratory capacity and increased mitophagy (as measured by LC3B and Tom20 colocalization) inside astrocytes and promoted RGC survival in microbead occlusion model of ocular hypertension (Hass and Barnstable, 2019)

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