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Blocks NNMT in fat cells In 3T3-L1 mouse fat cells, 30 M of 5-Amino-1MQ for 24 hours strongly lowered 1-MNA levels direct proof of NNMT inhibition (Neelakantan et al., Biochemical Pharmacology, 2018)

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This helps make more healthy red blood cells

Cryobiology 68, 251261

Little is known about how the levels of superoxide are regulated to maintain cell fate within the stem cell niche, but modulation of SOD and the ascorbateglutathione cycle are important in the control of this system

Warren RB, Weatherhead SC, Smith CH, Exton LS, Mohd Mustapa MF, Kirby B, Yesudian PD (2016) British Association of Dermatologists guidelines for the safe and effective prescribing of methotrexate for skin disease 2016