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However, understanding when high B12 levels may become problematic helps ensure safe, evidence-based supplementation under appropriate medical supervision
2 More recent work has clarified one striking pathway: growth hormone signaling activates the MEKERK cascade, which phosphorylates and inactivates the transcription factor PPAR, downregulating fat-specific protein 27 (FSP27, also called CIDEC)

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Unlike other vitamins, the absorption of vitamin B12 depends on a protein produced in your stomach, called the intrinsic factor

doi: 10.1016/S0140-6736(11)60205-5
