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Statistical summaries were performed using SAS software

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Daily supplementation with a combination of yeast beta-glucan (250 mg), vitamin D3 (3.75 g), vitamin B6 (1.05 mg), and zinc (7.5 mg) for 36 weeks was found to significantly alleviate cognitive fatigue in 65 ME/CFS patients, as evidenced by a randomized, double-blind, placebo-controlled trial [132]