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The typical course for B12 shots is to give a few injections in the first month (one per week) at 1000mcg per shot and then start to spread them out

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Clinical pharmacology and pharmacogenetics of prostaglandin analogues in glaucoma

Ng, J Sun et.al, Metabolic Studies of a Synthetic Lipolytic Domain (AOD 9604) of Human Growth Hormone, Hormone Research, February 2000