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MC4R in particular has been the focus of extensive research into its role in hypothalamic appetite circuits, sympathetic tone, and downstream neuroendocrine signalling making MT-2 a key pharmacological tool in these research areas

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To better quantify changes in individual metabolites associated with glycolysis and the TCA cycle, we conducted gas chromatography-mass spectrometry (GC-MS) on soleus muscles and D3 myotubes from WT, Alix / and ccOzz / mice

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