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Not surprisingly, employment of siponimod in SPMS has been observed to slow gray matter atrophy and reduce peripheral levels of neurofilament light chain (164)

Vitamin D, which is fat-soluble and a steroid hormone, is found in fish and mushrooms [71]

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114 Nevertheless, the transcriptional states of microglia remain incompletely understood, as microglia may respond to multiple pathological stimuli in the brain simultaneously
