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These mice have markedly reduced circulating IGF-1 levels (approximately 80% reduction), a slight reduction in body length while body mass was maintained (221, 304)

doi: 10.1210/endo.142.8.8324

Bergman RN, Kim SP, Hsu IR, Catalano KJ, Chiu JD, Kabir M, Richey JM, Ader M: Abdominal obesity: role in the pathophysiology of metabolic disease and cardiovascular risk

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Insulin-Like Growth Factor 1 CJC1295 and ipamorelin reliably raise serum IGF1, which supports follicle growth and sperm maturation by improving cellular growth in reproductive tissues

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