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doi: 10.3389/fimmu.2021.666223

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In the first case, the plasma levels of pro-nociceptive LA-derived octadecanoids and AA-derived eicosanoids were significantly increased and subsequent reduction with antinociceptive 3 oxylipins derived from EPA and DHA

10.1016/j.molp.2014.11.006 Mol Plant

These findings align with the idea that GPX4 is involved in sustaining the mitochondrial membrane potential under conditions of oxidative stress [224]

This paradoxical effect is referred to as antioxidant-induced reductive stress or disruption of redox homeostasis
