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[10] Hutchinsons melanotic freckle: Often known as the malignant freckle of Hutchinson

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According to the National Cancer Institute, up to 70 percent of melanoma cases in Black people and up to 46 percent in Asian people are ALMs

The most common dermoscopic parameter was a homogenous or nonhomogeneous diffuse pigmentation (97 of 129 [75%]) that was characterized by light brown, dark brown, and/or black color without other distinguishing aspects (Figure 1B)

Blood samples were then drawn at 0.5-, 1-, 1.5-, 2-, 3-, 4-, 6-, 8-, 12-, and 24-hours intervals following test product administration