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doi: 10.1053/j.gastro.2006.01.006

N Engl J Med 2000;343:180-4

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NO and S-Nitrosylation of Proteins Although many of the effects of NO are exerted via the activation of soluble guanylate, NO can also directly modify the sulfhydryl group of cysteine residues in proteins, a process termed S -nitrosylation

The lumen of the distal convoluted tubules was large and bordered by simple cubical cells with sphere nuclei in the middle or at the apex of the tubule walls (Figure 7A)