glutathione synthetase pathway The “Glutathione Pathway.” synthesis, γ-glutamyl pathway, Glutathione in Brain Disorders and
Description
Hogg JC

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Both the oxidation of nutrients in the mitochondria and the oxidation of nascent proteins in the ER generate toxic reactive oxygen species (ROS): in the mitochondria by electron leakage during oxidative phosphorylation (Murphy, 2009), and in the ER by catalysis of disulfide bond formation by ER oxidoreductase (ERO1) (Higa & Chevet, 2012)

Cells 43, 964973 10.14348/molcells.2020.0198 [DOI] [PMC free article] [PubMed] [Google Scholar] 141.Moulin V., Grandoni F., Castioni J
10.3322/canjclin.56.2.69 172 SchugZ
