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Modern biological theories of aging

a chemical agent is herein understood to be a defined chemical molecule, usually a smaller, non-polymeric molecule (e.g

This implies that systemic administration of such agents could inadvertently suppress antitumor immunity, canceling out the benefits of ROS-induced tumor killing

3.1 -oxidation Fatty acid -oxidation has been linked to platinum resistance (54), with genetic ablation of the homology box-containing developmental regulator NKX2-8 promoting fatty acid metabolism reprogramming and subsequent drug resistance in epithelial ovarian cancer cells in the adipose microenvironment (55)

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Once aggregated, those molecules are permanently denatured