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Randomized, placebo-controlled trial of Saforis for prevention and treatment of oral mucositis in breast cancer patients receiving anthracycline-based chemotherapy

Moreover, excess iron could promote the formation of reactive oxygen species (ROS), which can lead to oxidative stress and DNA damage, with cytokine-regulated inflammatory pathways and a central contribution from innate immune cells in the tumor microenvironment (360, 361)

[DOI] [PMC free article] [PubMed] [Google Scholar] 655.Ioni-Mndrican C.-B., Ziani K., Mititelu M., Oprea E., Neacu S.M., Moroan E., Dumitrescu D.-E., Roca A.C., Drgnescu D., Negrei C