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doi: 10.1016/j.pnpbp.2018.09.007

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The Epigenetic Oxidative Redox Shift Hypothesis of Aging To unify the free radical theory of aging with the decline of metabolism associated with reduced insulin signaling, as discussed above, Brewer proposed the epigenetic oxidative redox shift (EORS) hypothesis of aging (413415)

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Studies revealed that the copper compound could escalate the intracellular levels of Reactive Oxygen Species (ROS), precipitating oxidative stress

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Parkin overexpression attenuates A-induced mitochondrial dysfunction in HEK293 cells by restoring impaired mitophagy

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