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Oxidative Med Cell Longev 2018:9719584
187,188 Mechanisms of inflammaging Consensus features of inflammaging While the precise interpretation of senescent cell markers remains incomplete and requires further investigation, there is a consensus regarding certain essential characteristics of senescent cells, primarily focusing on the SASP (Table 1)
Principal Component Analysis (PCA) of elemental profiles (Figure 2B) revealed distinct metal associations in BAL and plasma samples, supporting the idea that multiple metals may act synergistically or additively in IPF onset or progression
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as NADPH oxidase and ion channel inhibitors
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