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The rationale focuses on local gut effects rather than systemic distribution

323 Passionflower has also been found to be as effective as the benzodiazepine drug midazolam (Versed) at relieving anxiety prior to dental surgery

Praxis (Bern 1994) 86:510523 Gollamudi R, Ali SF, Lipe G et al (1989) Influence of inducers and inhibitors on the metabolism in vitro and neurochemical effects in vivo of MDMA

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Researchers tracking how this evidence base matures can compare it with the companion assessment of whether current research supports cagrilintides role in lowering stroke risk, which weighs a similarly early evidence base for a different endpoint