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(PDF 229 KB) Additional file 7: Relation between gene expression changes associated with regional emphysema severity (Lm) and studies of TGF-related gene expression using GSEA

Hypoxia and TGF-beta drive breast cancer bone metastases through parallel signaling pathways in tumor cells and the bone microenvironment

Thus, FH offers an important opportunity to target therapies to prevent atherosclerosis (437), but FH remains under recognized with recent evidence suggesting that only 1-10% of subjects with FH have been identified (438)
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Although the limited ability of paclitaxel to cross the intact bloodbrain barrier initially suggested indirect mechanisms of action, research now indicates that paclitaxel can indeed reach brain tissue, particularly the hippocampus, at concentrations sufficient to induce neurotoxicity (Tang et al., 2022)
