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GLUTs exhibit K m values for glucose ranging from 0.5 to 7 mmol/l and V max from 5 to 50 nmol/min/million cells

10.1016/j.abb.2016.08.021 [DOI] [PMC free article] [PubMed] [Google Scholar] Kalyanaraman B, Cheng G, Hardy M, Ouari O, Bennett B, Zielonka J (2018) Teaching the basics of reactive oxygen species and their relevance to cancer biology: mitochondrial reactive oxygen species detection, redox signaling, and targeted therapies

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Glutathione supplementation can also be considered in resistant or recurrent melasma as part of adjunctive therapy
*Supraphysiologic dosing is anything over 1100 g (1.1 mg) although a 2013 paper exploring some of the extrathyroidal actions of iodine recommended at least a 3 mg daily intake of I 2 [3]

ROS-induced damage of lipids significantly affects membrane fluidity and permeability