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In particular, they frequently fail to account for age-associated changes, comorbidities, and human-specific pathological features (Vitek et al., 2020)

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doi: 10.1073/pnas.1000041107 32 HernandezS

The Gut-Brain Connection: How Your Microbiome Controls Sugar Cravings Your gut houses over 100 trillion bacteria that communicate directly with your brain through multiple pathways

These contaminants pose a significant and underestimated threat to human health [97]

Neurochem Res 27, 501505 (2002)