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Description
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ASS1 expression is downregulated in CHOL, GBM, KICH, KIRC, KIRP, and LIHC tumor categories, suggesting the feasibility of arginine depletion therapy
For instance, in mdx mice (a model of dystrophinopathy), an improved calcium handling resulting in lower intracellular calcium concentrations and enhanced cell survival have been shown in cultured cells [50]
Carnitine depletion in patients undergoing hemodialysis may lead to various conditions, such as muscle weakness and fatigue, plasma lipid abnormalities, and refractory anemia
These often appear when doses exceed recommended limits or when supplements are taken on an empty stomach
