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13 patients discontinued daratumumab due to progressive disease and 2 due to toxicity

Dual-compartment models commonly include central and peripheral distribution volumes with one or more elimination pathways

VEGF-A and Semaphorin3A: Modulators of vascular sympathetic innervation

doi: 10.1111/j.1742-481X.2008.00439.x

Red flags include: Unusual side effects Interactions with other medications Changes in your overall health If you notice any of these signs, call your oncology team right away

Interestingly, this study also found that cognitive performance was impaired in participants that had high RBC folate and serum vitamin B-12 within the low-normal range (median value = 383 pmol/L)