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Biomimetic textile dyes which are developed in 1970s are the most known synthetic ligands
A study (Hambright et al., 2017) showed that GPX4-knockout AD mouse models exhibited reduced hippocampal and cortical neuronal proteins and increased LPO, which were reversed by the lipophilic antioxidant vitamin E
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How much more evidence is required to convince stakeholders that the poor performance of antioxidants used in pre-ferroptosis era clinical trials was due to poor choices and a general lack of awareness regarding the precise role of RTAs as cell death suppressors