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Residual gastric content from dinner slows absorption, and circadian NNMT activity peaks in the evening mean the enzyme has already processed most of the days nicotinamide load

Infection control

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Vitamin B12 also helps keep you looking young because it keeps your hair from turning grey

Don't double up on doses to "catch up." If you frequently find yourself missing doses, it might be worth discussing with your healthcare provider whether your current schedule is realistic or if adjustments would be helpful

Heffernan MA, Thorburn AW, Fam B, et al