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If there is no response after the first injection, wait 24 hours and increase the dose by 2.5-10mcg

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Rats treated with the drug, as compared to a control group, showed significant improvement after less than one week of treatment, which continued for the remainder of the drug application and, for an additional 12 weeks after withdrawal from the drug, indicating sustained neurological amelioration of stroke-induced cognitive deficits

PMID: 47 GongYChenAZhangGShenQZouLLiJet al

Specifically, SAPs have been used for PNI recovery both as luminal fillers within nerve guidance conduits (Zhan et al., 2013