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ATM-deficient mice, worms, and cell models demonstrated accumulation of cytoplasmic DNA, hyperactivation of PARP1, and low NAD + levels 111,288

Other anti-FAP bispecific antibodies featured with FAP-targeting and immunomodulatory effects have also been developed [281]

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Source 44: Night blindness, vitamin A deficiency, and isotretinoin psychotoxicity Source 45: Unilateral calf pain in the pediatric emergency department Source 46: Cerebral ischemia probably related to isotretinoin Source 47: ACCUTANE (isotretinoin capsules) Source 48: Isotretinoin induced small vessel vasculitis: a life-threatening pulmonary-renal syndromea case report Source 49: Isotretinoin-induced encephalopathy Source 50: StatPearls: Creatine Phosphokinase Source 51: Arthritis precipitated by isotretinoin treatment for acne vulgaris Source 52: Isotretinoin-induced arthritis mimicking both rheumatoid arthritis and axial spondyloarthritis Source 53: Presumed Isotretinoin-Induced, Concomitant Autoimmune Thyroid Disease and Ocular Myasthenia Gravis: A Case Report Source 54: Analysis of musculoskeletal side effects of oral Isotretinoin treatment: a cross-sectional study Source 55: A rare cause of central hypothyroidism: oral isotretinoin treatment Source 56: Is Sex Good for Your Health