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In parallel, therapeutic strategies should focus on targeting the shared mechanisms of neurotoxicity, such as oxidative stress and neuroinflammation, while considering drug-specific interventions

doi: 10.1038/ncomms11190 195 ZhuYDoornebalEJPirtskhalavaTGiorgadzeNWentworthMFuhrmann-StroissniggHet al

We next addressed the role of p53 in FOXO4-DRI-mediated clearance of senescent cells

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By weeks eight to ten, he was tolerating short runs without the sharp pain that had defined his plateau