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Myth 1: Glutathione completely changes your natural skin color

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While cysteine readily oxidizes to form the disulfide cystine, cells contain less cystine than cysteine in the cytosol because the ubiquitous reducing agent, glutathione (which contains cysteine), effectively reverses the formation of cystine by a non-enzymatic reduction reaction

Translate this page into: Glutathione as a skin whitening agent: Facts, myths, evidence and controversies 1 , Deepashree Daulatabad 2 , Rashmi Sarkar 3 1 Skinnocence: The Skin Clinic, Gurgaon, Haryana, India 2 Department of Dermatology and STD, UCMS and GTB Hospital, New Delhi, India 3 Department of Dermatology and STD, MAMC and LN Hospital, New Delhi, India Correspondence Address : Sidharth Sonthalia Skinnocence: The Skin Clinic, C-2246, Sushant Lok-1, Block-C, Gurgaon - 122 009, Haryana India Abstract Keywords: Depigmenting, glutathione, hyperpigmentation, skin lightening, skin whitening Introduction A lighter skin tone has been considered a superior trait in most races, especially in women of Asian or African descent who have Fitzpatrick skin types IVVI

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These differing responses can be explained by understanding that GSH synthesis requires both glycine and cysteine, and both are provided by GlyNAC