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The angiopep-2 peptide that binds to low-density lipoprotein receptor-related protein-1 (LRP-1) was conjugated to paclitaxel via a succinyl group (named ANG1005) and applied to the treatment of glioma and metastatic breast cancer 82

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Here, we systemically demonstrate that GDIL drives acquired platinum resistance by inhibiting GSH degradation instead of increasing GSH synthesis, through GDIL/XRN2/CHAC1 pathways

Sherson D

Improved cardiac performance after ischemia in aged rats supplemented with vitamin E and alpha-lipoic acid