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Results: Both DP1 mRNA expression and DP1 promoter activity were reduced by treatment with the Sp1 inhibitor mithramycin A

Neuroprotective effect of curcumin is mainly mediated by blockade of microglial cell activation

Contextual Variables Published dosing patterns are influenced by factors such as: body weight of the research model species differences (rodent vs in-vitro systems) delivery method measurement endpoints (angiogenesis, fibroblast activity, inflammation markers, etc.) These variables limit direct comparison between studies

Circulation 2023;147:24253

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