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Various factors, including route of administration, dose, genetic polymorphism related to drug metabolism and polysubstance abuse, can modify the risk of methamphetamine toxicity [9]

Howe, A

doi: 10.3390/ijms23095144

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The pathophysiology is complex and involves genetic predisposition, environmental factors, oxidative stress, intrinsic metabolic dysfunctions, and abnormal inflammatory/immune responses

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