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Limited NVB dissection is applied since lateral dissection is not required

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[21] When treated with cyanocobalamin, patients with Leber's disease may develop serious optic atrophy, possibly leading to blindness, based on few case reports

The increased risk for these populations is due to low levels of consumption and difficulty with vitamin absorption
10.1038/s41586-020-2395-5 Nature 60 PowleyT

methylmalonyl-CoA, MCM