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ROS can damage cellular components such as lipids, proteins, and DNA, leading to cell death and loss of cardiac contractile function

2021;41:BSR20210427

Two most recent studies discovered unusually high peroxidation rates of low-abundance doubly-PUFA phospholpids in ferroptotically dying cells thus making decreased levels of these newly discovered substrates a promising additional biomarker of ferroptotic PL peroxidation [106,599]

(2020) 181:1188 e1

[DOI] [PubMed] [Google Scholar] 96.Thommen D.S., Koelzer V.H., Herzig P., Roller A., Trefny M., Dimeloe S., Kiialainen A., Hanhart J., Schill C., Hess C., et al

Gut-Brain axis and microbiota in PD pathogenesis In recent years, accumulating evidence suggests that the gut microbiota may play a significant role in the progression of PD