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Description
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Importantly, ceruloplasmin appears to lose its ability to inhibit MPO upon modification by HOCl [324]
This means that the more estrogens are conjugated by sulphation or glucuronidation, the lower the conversion into estrogen quinones, which can subsequently be converted into glutathione conjugates or lead to the formation of DNA adducts

Several trials have been conducted with NAC that specifically focused on congenital red cell diseases

doi: 10.1152/physrev.1978.58.2.317 76 RochetteLDogonGRigalEZellerMCottinYVergelyC
