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These symptoms point to widespread tissue damage caused by ranaviruses on the kidney, liver, spleen, and hematopoietic tissues

Not one or the other

Assessing the efficacy and mechanisms of Pycnogenol on cognitive aging from in vitro animal and human studies
10.1007/s00441-021-03559-9 122 LiuY.SunC.LiW.Adu-FrimpongM.WangQ.YuJ.et al (2019)
PMID: 23479233 Kepler, C.K., Markova, D.Z., Dibra, F., Yadla, S., Vaccaro, A.R., Risbud, M.V., Albert

Meanwhile, the Folate, having given up its methyl group, reverts to a base state so it can go pick up another methyl group and start the cycle all over again
