glutathione synthetase deficiency morphology Inborn errors in the metabolism of | Orphanet Journal of Rare Diseases Frontiers | Case report: A

Ubuka, T., Umemura, S., Yuasa, S., Kinuta, M

(2022) Cancer Res 82, 3209-3222

Thioredoxin reductases (TXNRDs) employ NADPH as an electron donor to revert oxidized TXN to a reduced dithiol, the oxidation status of which is critically implicated in regulating various cell behaviors including proliferation and apoptosis 51

Dosing Protocols There are no approved dosages or regimens for using Glutathione, but the following are common dose ranges: Subcutaneous Glutathione: Typical range: 100400 mg per dose Frequency: 13 times per week Intramuscular Glutathione: Typical range: 200600 mg per dose Frequency: 13 times per week Some clinicians may use up to ~1,000mg, depending on indication and patient tolerance Product Specifications And Handling Strength and form: Glutathione 200mg/ml injection solution Vial size: 30ml Route of administration: SQ (subcutaneous) or IM (intramuscular) Proper Storage And Beyond-Use Date Injectable Glutathione should be stored in the fridge from 36F to 46F

10.1055/s-0034-1384533 113 RazaviB

Eating a light meal before your appointment can help reduce this